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  • Thesis

  • Authors: Lu, Meiling (2006)

  • The metabolism, disposition, and toxicity of arsenic are dramatically different in humans and rats. To better understand the chemical and biochemical basis of these differences and the modes of action of arsenic, here I studied the interaction of arsenic species with hemoglobin (Hb) of both humans and rats. Fast gel filtration chromatography combined with inductively coupled plasma mass spectrometry, nanoelectrospray mass spectrometry, and tandem mass spectrometry methods have been developed to facilitate the study. The three metabolically reactive trivalent arsenic species, inorganic arsenite (iAs"), monomethylarsonous acid (MMA"), and dimethylarsinous acid (DMA"), showed increasing binding affinity with the Hb of rats and humans, with relative binding constants of 1:20:95 for rat...

  • Thesis

  • Authors: Haselton, Curt B. (2006)

  • A primary goal of seismic design requirements of building codes is to protect the life safety of building inhabitants during extreme earthquakes. First and foremost, this requires that the likelihood of structural collapse be at an acceptably low level. However, building codes and standards are empirical in nature, which results in the collapse safety of new buildings not being well understood. In this research, we develop the tools and methods to quantitatively assess the collapse risk of reinforced concrete (RC) special moment frame (SMF) buildings designed by the 2003 International Building Code. While RC SMF buildings are the focus on this study, the methodology and many of the tools can be used to assess any type of structural system. This rigorous analytical collapse assessme...

  • Thesis

  • Authors: Al-Shameri, Faleh Jassem (2006)

  • Recent years have witnessed an explosion in the amount of digitally-stored data, the rate at which data is being generated, and the diversity of disciplines relying on the availability of stored data. Massive datasets are increasingly important in a wide range of applications, including observational sciences, product marketing, and the monitoring and operations of large systems. Massive datasets are collected routinely in a variety of settings in astrophysics, particle physics, genetic sequencing, geographical information systems, weather prediction, medical applications, telecommunications, sensors, government databases, and credit card transactions. Data mining associated with massive datasets presents a major problem to the serious data miner. Datasets on the scale of terabyt...

  • Thesis

  • Authors: Fu, Zhe (2006)

  • The code reuse problem is a common software engineering problem in scientific computing. As a prevailing programming language in many scientific fields, Fortran does not provide support to address this problem. One particular reason is that Fortran lacks the support for generic programming. By applying programgeneration techniques, we developed two approaches to address the code reuse problem. The first approach is to design a program generator for the equation-based specification of subroutines that can be generic in the dimensions of arrays, parameter lists, and called subroutines. We apply that approach to a real-world problem in scientific cpmputing, which requires the generic description of inverse ocean modeling tools. on addition to a compiler that can transform generic speci...

  • Thesis

  • Authors: Dang, Jiangbo (2006)

  • Due to the convergence of industrial demands for business-process and supply-chain management and recent results in multiagent systems, autonomous software services, and the Semantic Web, Web services are becoming the main focus for the next generation of the Internet. They will behave like intelligent agents by composing themselves cooperatively into workflows. A workflow is a set of services that execute by carrying out specified control and data flows. Agents are persistent active entities that can perceive, reason, and act in their environment, and communicate with other agents. Agents can interact autonomously across enterprise boundaries and, when thought of as services, provide a new way to achieve programming-in-the-large. Agents interact with other agents through negotiatio...

  • Thesis

  • Authors: Ma, Dehong (2006)

  • This is a study of tracking moving objects robustly and efficiently from a video stream. Video object tracking aids higher level image analysis by providing richer image information more efficiently. It can find many applications in smart video surveillance, video conferencing, human computer interface, traffic measurement, image stabilization, video compression, etc. However, it is still an open problem due to the difficulties from over/under segmentations, the different views of a moving object, the morphology of non-rigid objects, the occlusions of multiple moving objects, lighting changes, shadows, reflections, etc. These difficulties often result in frequent object loss, high false alarm ratio, and other problems. In this thesis we describe a Bayesian framework, combining ...

  • Thesis

  • Authors: Greene, Gary Gordon, Jr. (2006)

  • Torsion can be a significant action in many structural members that are part of civil engineering infrastructure. Gravity loads can induce torsional stresses in curved bridges and spandrel beams. Seismic loads can induce cyclic torsion combined with other actions in the beams and columns of bridges with outriggers. Reliable models are needed to predict the effect of torsional stresses on a reinforced concrete (RC) member's hysteretic load-deformation response, and also on the monotonic behavior at service and ultimate load levels. Little previous research has focused on the hysteretic behavior of RC members under cyclic torsion and torsion combined with other actions. This research study was intended to improve the understanding of the behavior of such members and provide analytical...

  • Thesis

  • Authors: Hung, Eugene (2006)

  • ReAgents are remotely executing agents that customize Internet applications for thin/weak clients. A reAgent is essentially a "one-shot" mobile agent that acts as an extension of a client, dynamically launched by the client to run on its behalf at a remote, more advantageous, location. ReAgents simplify the use of mobile agent technology by transparently handling data migration and run-time network communications, and provide a general interface for programmers to more easily implement their application-specific customizing logic. This is made possible by the identification of useful remote behaviors, i.e., common patterns of actions that exploit the ability to process and communicate remotely. Examples of such behaviors are filters, monitors, cachers, and collators. In this dissert...

  • Thesis

  • Authors: Kong, Linggang (2006)

  • Due to wind and wave actions, ship impacts, high-speed vehicles, and other sources of loading, structures such as offshore platforms, tall buildings, high-rise bridges, and electric transmission towers undergo significant torsional loads. Insufficient design of the foundations of these structures against torsional loads may affect the serviceability and safety of these structures. The objectives of this research are: (1) through a series of centrifuge model tests, to build basic understanding of load sharing mechanisms in pile groups subjected to torsion, pile-soil-pile interactions in torsionally loaded pile groups, and the load-deformation coupling effects in the pile groups and (2) to develop a model to analyze the problems in a rational manner. A series of centrifuge tests, i...