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Review: fish collagen: extraction, characterization and application in wound healing and drug delivery
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Tóm tắt
Collagen is a natural protein present in the animal and human body. It is in natural fibrous and can be found in the connective tissue and flesh of mammals, approximately 25 - 35 wt.% of total human protein. Collagen is abundant in fibrous tissues such as bones, cartilage, tendons, blood vessels, ligaments, skin, cornea, aortic disc, and intestines. Fish collagen is currently being studied as a new biological substitute for collagen from animals. It is extracted from by-products (scales, skins, bones, etc.) by biochemical or biological methods is safe, has high adsorption, high compatible. The factors influencing on the extraction process include temperature, time, concentration of ingredients, etc. The fish collagen is usually collagen type I with a fibril structure. Each unit of collagen is tropocollagen consisting of three polypeptide chains twisted together. Depending on the source of ingredients, the composition of amino acids, denaturation temperature, the sequence of amino acids, structure, morphology, molecular weight, extraction yield, etc. of obtained collagens are different. This paper reviews the extraction and characterization of fish collagen from products after fish processing by chemical or biochemical methods. The applications of fish collagen in wound healing and drug delivery are also reviewed.
Mô tả
Vietnam Journal of Science and Technology Vol. 62, No. 1
Tác giả
Nguyen, Thuy Chinh
Thai, Hoang
Người hướng dẫn
Nơi xuất bản
Nhà xuất bản
Viện Kỹ thuật Nhiệt đới, Viện Hàn lâm Khoa học và Công nghệ Việt Nam
Năm xuất bản
2024-02
ISSN tạp chí
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Từ khóa chủ đề
Chemical method , Natural protein , Collagen , Drug delivery , Extraction , Biochemical method , Wound healing
URI
Tài liệu tham khảo
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Tệp tin
Nguyen Thuy Chinh, Thai Hoang.pdf
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