Ấn phẩm:
Ergostane steroids from Aspergillus sp. M904 in Vietnam
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Seven ergostane steroids were isolated from the cultures of Aspergillus sp. M904, an endophytic fungus isolated from the marine sediment sample collected at a depth of ten meters in Binh Dinh, Vietnam. These compounds include 5α,6α-epoxy-(22E,24R)-ergosta-8(14),22-diene-3β,7α-diol (1), 5α,6α-epoxy-(22E,24R)- ergosta-8(9),22-diene-3β,7α-diol (2), ergosterol (3), ergosterol peroxide (4), 3β,5α,6α-trihydroxy-ergosta- 7,22-diene (5), 3β,5α,9α-trihydroxy-ergosta-7,22-diene-6-one (6), 3β-hydroxy-5α,9α-epoxy-ergosta-7,22- dien-6-one (7). Their structures were identified through MS and NMR data analyses. All compounds were evaluated for their antimicrobial activity against a panel of clinically significant microorganisms. Compounds 1–7 had inhibitory activity against from one to six tested strains with MIC values from 64–256 µg/mL.
Mô tả
Vietnam Journal of Marine Science and Technology, Vol. 24, No. 4
Tác giả
Trinh, Thi Thanh Van
Nguyen, Mai Anh
Vu, Van Nam
Nguyen, Thuy Linh
Le, Thi Hong Minh
Brian, T. Murphy
Doan, Thi Mai Huong
Pham, Van Cuong
Người hướng dẫn
Nơi xuất bản
Nhà xuất bản
Viện Hàn lâm Khoa học và Công nghệ Việt Nam
Năm xuất bản
2024-12
ISSN tạp chí
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Từ khóa chủ đề
Aspergillus , Steroid , Ergostane , Argostane