Ấn phẩm:
A study on biological activities of Bouea macrophylla Griff leaf extract
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Tóm tắt
Bouea macrophylla in the family Anacardiaceae is a prominent fruit in Southeast Asia, especially in Vietnam with several prospects. This study focused on the bioactive components and biological effects of B. macrophylla ethanol leaf extract. Phytochemical analysis revealed various compounds including polyphenol, tannin, saponin, reducing agent, flavonoid, and essential oil in the extract. The DPPH assay showed the remarkable antioxidant capacity of the extract (IC50 = 6.4 ± 0.08 μg/ml), which is stronger than ascorbic acid (IC50 = 9.35 ± 0.12 μg/ml). The disc diffusion method and minimal inhibitory concentration test displayed the significant antibacterial ability of the extract against Listeria monocytogenes, Escherichia coli, Pseudomonas aeruginosa, Salmonella typhimurium, and Bacillus cereus at the range from 10 - 15 mg/ml, but no activity against Staphylococcus aureus. Moreover, the MTT assay was performed the noticeable anticancer activity of the extract in HepG2 (IC50 = 72.33 ± 0.68 μg/ml), and MCF-7 cells (IC50 = 50.25 ± 1.36 μg/ml). Taken together, this study indicated the effects ofB. macrophylla ethanol leaf extract from Vinh Long Province, Vietnam on antibacterial, antioxidant, and anticancer properties. Therefore, B. macrophylla possibly is used in the food industry and medicine.
Mô tả
Vietnam Journal of Biotechnology, Vol. 20, No. 2
Tác giả
Pham, Thi Hai Ha
Tran, Kien Cuong
Nguyen, Thi Thu Nha
Nguyen, Phan Hoang Lan
Nguyen, Huu Thuan Anh
Bach, Long Giang
Pham, Minh Quan
Tran, Quoc Toan
Pham, Quoc Long
Nguyen, Thanh Luan
Người hướng dẫn
Nơi xuất bản
Nhà xuất bản
Viện Công nghệ sinh học, Viện Hàn lâm Khoa học và Công nghệ Việt Nam
Năm xuất bản
2022-06
ISSN tạp chí
Nhan đề tập
Từ khóa chủ đề
Antibacterial , Anticancer , Antioxidant , Bioactive compounds , Bouea macrophylla
URI
Tài liệu tham khảo
Thông tin bản quyền
Tệp tin
Pham Thi Hai Ha, Tran Kien Cuong, Nguyen Thi Thu Nha, Nguyen Phan Hoang Lan, Nguyen Huu Thuan Anh, Bach Long Giang, Pham Minh Quan, Tran Quoc Toan, Pham Quoc Long, Nguyen Thanh Luan.pdf
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