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  • Authors: Doucett, Elisabeth (2010-06)

    The article discusses the top ten ways that libraries can stay relevant to their users through strategies that incorporate societal trends. The author briefly relates her experience as a public library director, who spent a great deal of time searching out ways to keep her library relevant in today’s fast-changing environment.
  • Authors: Haddad, Reda Nassif (2006)

    3-tier Service Level Agreement with automatic class upgrades. (Under the direction of Dr. Yannis Viniotis). Tremendous efforts have been spent on devising mechanisms that would provide Quality of Service (QoS) needed by various applications, and network operators have spent a lot of resources trying to fit their networks with differentiated services capabilities. One of the Service Level Agreements (SLA) promising to sell these QoS services is the "triple play" SLA, bundling 3 classes of services targeting voice, data and video. In particular, circuit switched network operators envision the triple play SLA as essential to revenue maintenance, customer retention, and growth. It is the...
  • Authors: Schumacher, Steve (2011-05)

    Steve Schumacher is a management consultant, trainer and public speaker with more than 25 years of experience in numerous industries throughout North America, including aggregates operations. In this article, he introduces five easy steps that managers not only raise productivity of their employees, but also make them feel more included in the business and take morale to high levels.
  • Authors: Finnie, Scott (2010-10)

    In this article the author offers his perspective regarding the five information technology (IT) business trends for 2011
  • Authors: J. Laster, Stephen (2011-05)

    The author, a chef information officer of Harvard Business School, discusses the six building blocks of success in higher education information technology (IT) leadership, and the challenges for IT leader in higher education
  • Authors: Dixon, James Brandon (2006)

    Collecting microlymphatics play a vital role in promoting lymph flow from the initial lymphatics in the interstitial spaces to the large transport lymph ducts. In most tissues, the primary mechanism for producing this flow is the spontaneous contractions of the lymphatic wall. Individual units, known as lymphangion, are separated by valves that help prevent backflow when the vessel contracts, thus promoting flow through the lymphatic network. Lymphatic contractile activity is inhibited by flow in isolated lymphatics, however there are virtually no in situ measurements of lymph flow in these vessels. Initially, a high speed imaging system was set up to image in situ preparations at 500...
  • Authors: Bao, Yu (2006)

    The mechanical behavior of saturated soil is mainly governed by the interaction between the soil skeleton and the pore fluid, and this interaction may lead to significant loss of strength known as liquefaction under seismic loadings. The main objective of this thesis is to develop and implement a cyclic constitutive model capable of modeling soil skeleton dilatancy during earthquake excitation. The constitutive model is based on the fuzzy-set plasticity theory and enhancement is made on the description of dilatancy behavior under cyclic loading. A robust Biot formulation, in which the governing equations of motion of the soil mixture are coupled with the global mass balance equations,...
  • Authors: Eastwood, Erin L. (2006)

    Drug target identification is a time consuming stage of the drug discovery process. Chemical genomics offers a solution to this hurdle. In chemical genomics, a target specific chemical ligand is applied on a genomic scale. This technique was used to identify the molecular target of anti-proliferative agents using changes in mRNA transcript levels upon treatment. Whole-genome transcription profiling experiments employed the eukaryotic model organism Saccharomyces cerevisiae for small-molecule perturbation experiments in addition to traditional genetics. Chemical genomics was used to examine the molecular target of borrelidin, a macrolide with conflicting published biological activitie...
  • Authors: Nguyen, Van Tung; Nguyen, Thi Kim Lien; Nguyen, Huy Hoang (2021-06)

    Advances in next generation sequencing allow us to do DNA sequencing rapidly at a relatively low cost. Multiple bioinformatics methods have been developed to identify genomic variants from whole genome or whole exome sequencing data. The development of better variant calling methodologies is limited by the difficulty of assessing the accuracy and completeness of a new method. Normally, computational methods can be benchmarked using simulated data which allows us to generate as much data as desired and under controlled scenarios. In this study, They compared three variant calling pipelines: Samtools/VarScan, Samtools/Bcftools, and Picard/GATK using two simulated datasets. The result sh...
  • Authors: Harper, Lois (2006)

    From the variety of agent communication languages that have been proposed since the early 1990's, it can be seen that there is no general agreement on what constitutes a necessary core of semantics for agent communication languages. This has led some researchers to observe that agent communication languages have been implemented ad hoc. This dissertation develops and evaluates an approach towards representing the semantics of agent communication languages explicitly in the notation of conceptual graphs. The speech act theories of Austin, Searle and Habermas that are cited as having motivated the semantics of some agent communication languages are also represented in conceptual graph n...