Browsing by Author Pickering, Brian F.
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Mono- and multipathogen anti-peptide antibodies for passive immunization or treatment of the biothreat agents Bacillus anthracis, Yersinia pestis, and Francisella tularensis
As etiological agents of anthrax, plague, and tularemia, which can be used as biological weapons, the United States Centers for Disease Control and Prevention (CDC) has classified Bacillus anthracis, Yersinia pestis, and Francisella tularensis as Category A pathogens. Currently, the response to a bioterrorist attack utilizing these agents would be largely reactive as there are no approved vaccines for general public use. Post-exposure antibiotic treatment is effective if it is administered shortly after exposure to the pathogens and due to their long term treatment schedule, the antibiotics tend to be associated with well-known severe side effects. Antibodies that are highly specific ...