Browsing by Publishers Case Western Reserv University

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    • Thesis

    • Authors: Struk, Peter M. (2006)

    • This dissertation presents a "lumped" two-phase (solid and gas) model of transient catalytic combustion suitable for isolated channels or monolith reactors. The gas-phase is quasi-steady relative to the transient solid. Axial diffusion is neglected; lateral diffusion, however, is accounted for using transfer coefficients. The solid phase includes axial heat conduction and external heat loss due to convection and radiation. The combustion process uses detailed gas-phase and surface reactions. The gas-phase model becomes a system of stiff ordinary differential equations while the solid-phase reduces, after discretization, into a system of stiff ordinary differential-algebraic equations....

    • 3205028.PDF.jpg
    • Thesis

    • Authors: Zhang, Wei (2006)

    • Doublesex (dsx) and dsx-related genes encode a novel class of transcription factors conserved among metazoans. The members of this family play a critical role in sex differentiation across species from Caenorhabditis elegans to humans. Mutations or deletions of these genes are associated with intersexual abnormalities, including a class of human birth defects termed "9p syndrome". This thesis is focused on the dsx gene from Drosophila melanogaster, the archetype of this class. Sex-specific RNA splicing leads to male and female isoforms, designated DSXM and DSXF. Biochemical and genetic studies of the DM domain and the female-specific C-terminal domain are presented. The importance of ...